Job Board
LogoLogo

Get Jobs Tailored to Your Resume

Filtr uses AI to scan 1000+ jobs and finds postings that perfectly matches your resume

Sanofi Logo

Associate Scientist - Computer-Aided Drug Discovery (CADD), Integrated Drug Discovery

Sanofi

Salary not specified
Jul 4, 2025
Cambridge, MA, US
Apply Now

The job is looking to solve the problem of speeding up drug discovery and development to find answers for patients and their families by providing computational chemistry support.

Requirements

  • Proficient in the use of modeling techniques (machine learning, and absolute binding free energy calculations, metadynamics and Monte Carlo simulations) and capable of developing and automating workflows.
  • Demonstrated skills in developing and implementing AI-based algorithm and method for property predictions.
  • Recognized as a technical expert with growing scientific and subject matter expertise and innovative contributions.
  • Emerging track record as a contributor providing quality science that forms the basis for publications, presentations and patents and involvement in professional society.

Responsibilities

  • Provide computational chemistry support, including cheminformatics, structure and ligand-based hit identification and lead optimization.
  • Perform in-depth analysis of project data, such as HTS results, biochemical assay results, biophysical data, and propose new studies and experiments.
  • Develop and apply predictive models to support medicinal chemistry efforts in the design and prioritization of novel bioactive compounds based on emerging data.
  • Use knowledge and experience to proactively collaborate with other team members to design target compounds which address challenges and/or test a hypothesis.
  • Conduct and analyze patent searches, assess the patentability of designed compounds, assist with filing of patent applications.
  • Champion new modeling techniques and participate in software evaluation and recommendation.
  • Collaborate with data scientist to implement predictive models/tools within informatics platform.

Other

  • Master’s degree in physical organic chemistry, biophysics, medicinal chemistry or related field plus 3 years of related experience.
  • Understand and articulate the scientific rationale of the project to other scientists.
  • Provide formal and informal mentoring of computational tools within project team and medicinal chemists in the department.
  • Actively participate in project team meetings, communicate in a clear and precise manner, raise questions, and contribute to the project.
  • Work closely with medicinal chemistry & structural biology scientists with shared ownership and accountability of project.
  • Communicate and interact with staff members in a professional and courteous manner.
  • Adapt to changes and challenges in a productive and professional manner.
  • Conduct work according to HSE guidelines and adhere to all mandatory company compliance requirements.
  • Act as an ambassador for the department and company, attend appropriate scientific meetings to increase knowledge and stay current with journal and patent literature.