Mass General Brigham is seeking a Bioinformatics Specialist to implement and maintain hardware and software infrastructure for deep learning, high-dimensional image analysis, and data management to extract meaningful insights from multimodal datasets.
Requirements
- Proficiency in Python, R, Java/Groovy and Bash scripting.
- Familiarity with containerized environments (e.g. Docker, Apptainer).
- Familiarity with machine learning / AI for image and genomic data analysis.
- Experience working in Unix/Linux environments and using HPC/cloud-based pipelines.
- Strong organizational skills for handling large and complex datasets.
- Ability to collaborate effectively in a multidisciplinary research team.
- MSc or PhD (or BSc with equivalent experience) in Bioinformatics, Computational Biology, Biostatistics, or related field.
Responsibilities
- Develop and maintain data pipelines for large-scale imaging and sequencing datasets.
- Set up and maintain multi-user GPU/HPC infrastructure for large-scale multi-omics analysis and deep learning model training/inference.
- Manage data storage, versioning, and retrieval in compliance with FAIR data principles.
- Maintain documentation and reproducible workflows using Snakemake, Nextflow, or WDL.
- Develop and implement workflows for Lunaphore COMET and Singular Genomics G4X multiplexed immunofluorescence image analysis.
- Process and analyze high-dimensional imaging datasets using QuPath, ImageJ, Cellpose, and other computational tools.
- Conduct Next-Generation Sequencing (NGS) analysis, including variant calling, gene expression analysis, and pathway enrichment studies.
Other
- MSc or PhD (or BSc with equivalent experience) in Bioinformatics, Computational Biology, Biostatistics, or related field.
- Strong organizational skills for handling large and complex datasets.
- Ability to collaborate effectively in a multidisciplinary research team.
- Onsite work required
- 40 scheduled weekly hours
