Ann & Robert H. Lurie Children’s Hospital of Chicago is seeking a Clinical Data Analyst to support the goal of providing comprehensive -omics analysis to pediatric patients treated at Lurie Children’s, with a focus on high complexity genetic testing methodologies and analysis of genomic data.
Requirements
- Ph.D in a field directly related to human genetics and genomics required
- Experience analyzing Next-Generation Sequencing data (whole genome/exome, RNAseq and custom panels) with commonly used bioinformatics tools and databases preferred (e.g. Mutation Surveyor, ClinVar, OMIM, HGMD).
- Experience in Next-Generation Sequencing or molecular biology bench work highly preferred
- Strong technical documentation capabilities
- Demonstrated analytical and problem-solving skills with good attention to details
- Experience working in a team-based environment with strong work ethic, time management skills, and proven productivity
- Excellent verbal and written communicator
Responsibilities
- Performs technical quality review of data from high complexity genetic testing methodologies such as Next-Generation Sequencing (NGS), MLPA, microarrays, fragment analysis and Sanger sequencing.
- Using existing databases and newly-developed analysis tools, performs technical and clinical interpretation of genetic sequence alterations identified through Next-Generation Sequencing (NGS).
- Performs initial analysis/quality review of test data and assists the Genetic Counselors/Medical Directors in drafting preliminary patient reports for molecular genetic tests.
- In collaboration with laboratory technologists, identifies opportunities to improve data accuracy/integrity by evaluating, refining and improving analysis/variant interpretation workflows, and assists in the continued development of standard operating procedures.
- Recognizes the clinical significance of each test performed, maintains the confidential and sensitive nature of patient information and results, and adheres to HIPAA regulations for transactions, security and confidentiality, and reports results within established time frames.
- Maintains a professional level of knowledge of molecular biology and genetics to properly analyze molecular genetic test results; in particular, in the context of abnormal or atypical findings, by conducting comprehensive literature review.
- Contributes to new test method and technology development and expansion of services provided by the laboratory via direct clinical lab work and/or review of test data generated during method development and validation.
Other
- PhD: Genetics (Required)
- Travel requirements not specified
- Strong work ethic, time management skills, and proven productivity required
- Excellent verbal and written communicator required
- Ability to work in a team-based environment required
