Generate Biomedicines is seeking a Research Associate II to join their CryoEM Group to generate large-scale protein structural datasets, contributing to the acceleration of drug discovery through advanced imaging technologies.
Requirements
- Hands-on experience in basic wet lab techniques, including pipetting, buffer preparation, and protein purification.
- Strong understanding of protein chemistry concepts, such as molarity, protein concentration, and buffer formulation.
- Familiarity with structural biology techniques and CryoEM sample preparation.
- Hands-on experience with liquid handlers (Tecan, Hamilton).
- Prior exposure to CryoEM workflows or microscope operation with SerialEM.
Responsibilities
- Perform protein purification, complexation, vitrification, and clipping, ensuring high-quality sample preparation for CryoEM.
- Load and operate CryoEM microscopes, executing data collection with automated workflows.
- Collaborate with multidisciplinary teams to support high-throughput protein structure determination.
- Follow standard operating procedures (SOPs) and contribute to process optimization.
- Document experimental data and report findings in internal databases.
Other
- MSc in Biochemistry, Structural Biology, Biophysics, Molecular Biology, Chemistry, or a related field and 0-2 years of experience, or a BSc in Biochemistry, Structural Biology, Biophysics, Molecular Biology, Chemistry, or a related field with 2-4 years of related experience.
- Ability to work in a fast-paced, collaborative research environment.
- Strong attention to detail and ability to troubleshoot technical issues.
- This is a full-time Contractor position budgeted through 12/19/2025.
- This position will be located in our Andover, MA location 5 days/week.
