At Johnson & Johnson, we are seeking to advance Precision in Measurement for the Neuroscience Precision Measures team by developing transformational medicines for Neurodegeneration, Neuropsychiatry and Ophthalmology. The Director, Computational Multiomics, Neuroscience will influence the future success of our Precision Neuroscience portfolio by ensuring measurement discovery and development strategies are deeply aligned and evolve over the development lifecycle.
Requirements
- Extensive background working hands-on deriving insights from high-dimensional molecular data, particularly transcriptomic, genetic, proteomic, and/or single cell data.
- Familiarity with genomics, human genetics and disease biology in Neurodegeneration and/or neuropsychiatry
- Experience and familiarity with electronic health record derived phenotypes.
- Ability to write manuscripts for publication and has maintained a record of high-quality peer reviewed publications and oral presentations in a relevant field.
- Strong analytical and problem-solving skills, as well as organizational and time management skills.
- Ability to translate data into information and strategies into executable action plans.
- Computational Neuroscience experience is a plus.
Responsibilities
- Lead a team of 2 computational scientists in the application of large-scale multiomics and genetic capabilities to support our pipeline and advance data and technological approaches in bioinformatics & integrative data analytics.
- Partner with Neuroscience Discovery on strategy and process for evaluating target opportunities from the perspective of cutting-edge genetics, bioinformatics, biosignatures, brain biology, and mechanism, drawing upon a combination of internal and external human data resources.
- Partner with Clinical Development, Global Regulatory Affairs, Data Science, Patient Reported Outcomes, Statistics and other core functions in Precision Measures (including Biomarkers & Imaging) to contribute to holistic measurement plans (across molecular, imaging, digital, clinical and other measures) for our compounds in development.
- Develop relationships with key scientists and clinicians externally and with internal stakeholders to map target mechanisms to human genetics and brain biology with a view towards different indications or patient populations and develop forward looking data strategies along the path to launch.
- Establishing the team’s computational multiomics strategy across the portfolio from discovery through development, communicating that strategy effectively to stakeholders and leadership.
- Create a purpose driven culture in which decisions and actions are strategically informed by patient, customer and employee needs by aligning Johnson & Johnson’s Credo and Leadership Imperatives with the strategies and goals of the team and enterprise.
Other
- PhD with 8 years of progressive experience in a computational or physical science with prior application of advanced methods to the life sciences. A degree in a biological science with extensive application of advanced analytic methodologies will also be considered.
- Experience in leading interdisciplinary projects teams including scientists, data analysts and clinicians.
- Internationally recognized track record of scientific contributions with first author publications in high-impact journals.
- A track record as a people manager in an industry research environment.
- Demonstrated interpersonal skills with the ability to work effectively with an interdisciplinary team, including laboratory scientists, bioinformaticians, statisticians, and data analysts.
