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Director, Product Management - BioPharma

Guardant Health

$155,300 - $251,250
Oct 9, 2025
Palo Alto, CA, US
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Guardant Health is looking to solve the business problem of leading the strategy, development, and commercialization of Guardant’s biopharma-focused diagnostics portfolio, ensuring products are clinically impactful, scientifically rigorous, and aligned with the needs of biopharma partners.

Requirements

  • 8+ years of experience in product management, medical affairs, or biopharma strategy within oncology diagnostics or precision medicine
  • Proven success in launching and scaling diagnostic or healthcare products
  • Strong understanding of liquid biopsy, molecular diagnostics, and biomarker-driven oncology
  • Experience in companion diagnostics, biomarker development, or clinical trial integration
  • Familiarity with payer dynamics, evidence generation, and reimbursement strategies

Responsibilities

  • Define and execute a comprehensive product strategy aligned with Guardant’s biopharma business objectives and oncology roadmap
  • Lead cross-functional teams to design, develop, and deliver best-in-class assay and digital products for therapy selection and disease monitoring
  • Translate market insights and partner needs into actionable product plans, identifying unmet needs and prioritizing opportunities
  • Serve as the primary product liaison to the biopharma business unit, ensuring alignment with biomarker-driven trials, companion diagnostics, and regulatory strategies
  • Drive co-development partnerships and data generation initiatives to support product innovation and reimbursement
  • Monitor emerging trends, technologies, and competitive activity to inform product differentiation and future roadmap
  • Ensure products integrate seamlessly into oncology workflows—physician, nurse, and patient—to maximize adoption and usability

Other

  • Leadership position reporting to our Senior Director of Product Management.
  • Viable candidates will have deep expertise in oncology diagnostics, and a passion for driving innovation at the intersection of medicine, product strategy, and biopharma collaboration.
  • While not a requirement, this is an ideal opportunity for clinically-trained MDs, PhDs, or MD/PhDs to work at the forefront of oncology diagnostics.
  • Exceptional communication, analytical, and leadership skills with the ability to influence across scientific, clinical, and commercial domains
  • All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays.