Eli Lilly and Company is seeking a Human Genomics and Translational Data Sciences Lead to drive human genetics, proteomics, and exploratory clinical research for the treatment of diabetes, obesity, and cardiometabolic diseases
Requirements
- PhD or equivalent in Human Genetics, Epidemiology, Clinical Informatics, or related field
- Prior experience with multiple in human genetics workflows including analysis of WGS, WES, and genotyping data for association analyses, polygenic risks score analysis, and analysis of rare variants
- Prior experience working with clinical and observational biomedical informatics data sets, including data from clinical trials, EHRs, and large biobanks
- Prior experience with clinical/diagnostic genetics, including application of ACMG criteria for annotation of variant pathogenicity
- Strong track record of publications in top-tier journals
- Experience with JIRA, Confluence, Git, code review, and other documentation tools
- Ability to perform hands-on execution of human genetic analyses as needed
Responsibilities
- Provide scientific leadership and strategic vision in human genetics, proteomics, population data science, and clinical informatics to position Lilly at the forefront of genetics for diabetes, obesity, and complications
- Lead and mentor a team with diverse computational background
- Develop and implement strategies to optimally use public large-scale genetic/genomic resources and integrate with patient-derived data from clinical trials to provide novel insights for Lilly’s portfolio
- Lead efforts to analyze whole genome sequencing and proteomics data from clinical trial participants
- Align with DOCTA’s strategic priorities and drive data-driven innovative approaches to identify and validate novel therapeutic targets
- Spearhead cross-functional initiatives to translate genetic/genomic findings into actionable insights that inform drug discovery, biomarker development, and clinical trial design
- Implement industry-standard procedures for scientific project execution and documentation
Other
- MD + PhD preferred
- Demonstrated success in building, mentoring, and managing scientific teams
- Strong collaborative approach with outstanding communication and interpersonal skills to engage cross-functional teams and external partners
- Ability to prioritize and manage multiple competing priorities within a fast-paced environment
- Demonstrated ability to lead and manage successfully within a matrixed organization
