Neurocrine Biosciences is seeking to gain hands-on experience in gene therapy product development, specifically focusing on drug product formulation and manufacturing process design to accelerate the development of life-changing treatments for patients with neurological, neuroendocrine, and neuropsychiatric disorders.
Requirements
- Required degree or field: Pharmacology, Bioengineering, Biochemistry, Biology related field
- Prior experience in the pharmaceutical or biotechnology industry would be an asset but is not required
- Familiarity with biopharmaceutical technologies, physical and life sciences, product development, and regulatory approval processes is desirable
- Executing and analyzing DP analytical assays relevant to AAV programs, including dPCR/ddPCR, ELISA, thermal stability assessments, dynamic light scattering (DLS), and other characterization techniques.
- Supporting the development and optimization of AAV-specific analytical methods while contributing to broader gene therapy and biologics analytical capabilities.
- Analyzing and interpreting experimental data to draw scientifically sound conclusions and guide subsequent experimental work.
- Lab Work Requirements: Full-time
Responsibilities
- Supporting a range of Pharmaceutical Development (PD) activities with a primary focus on AAV formulation development, including execution of analytical assays to assess vector stability and compatibility with excipients.
- Designing, conducting, and documenting experiments to evaluate AAV formulation robustness, product stability, and process performance under various stress conditions.
- Executing and analyzing DP analytical assays relevant to AAV programs, including dPCR/ddPCR, ELISA, thermal stability assessments, dynamic light scattering (DLS), and other characterization techniques.
- Supporting the development and optimization of AAV-specific analytical methods while contributing to broader gene therapy and biologics analytical capabilities.
- Analyzing and interpreting experimental data to draw scientifically sound conclusions and guide subsequent experimental work.
- Preparing clear, concise presentations and technical reports to communicate experimental findings and recommendations to internal project teams.
- Completing a special project focused on AAV formulation and PD analytical development, culminating in a presentation of key findings and recommendations.
Other
- Pursuing an undergraduate degree with an interest in biotechnology
- Good verbal and written communication skills
- Ability to think creatively and be a team player
- Offer flexibility with a willingness to work on multiple projects simultaneously
- Ability to commit to a 10-week, full-time summer program
