The Turner Lab at WashU in St. Louis focuses on advancing the emerging field of Precision Genomics, which aims to determine all possible relevant genomic variation within an individual to the precise nucleotide. This field addresses critical challenges in genomic interpretation and translation, including interpretation of noncoding variation, variants missed by current technologies, speed and efficiency of genomic workflows, combined effects of rare and/or common multi-hit variants, and gene × environment interactions.
Requirements
- Experience with regulatory genomics, noncoding variant interpretation, or genome assembly/structural variant detection.
- Proficiency in one or more of the following: next-generation sequencing analysis, statistical genetics, genome editing, or functional genomics.
- Experience with high-throughput molecular biology assays.
- Experience with complex functional experiments.
- Background in machine learning, AI, or data integration for genomic datasets.
- Familiarity with gene-environment interaction studies.
- Experience with high-performance computing and parallel computing techniques including working in the cloud.
Responsibilities
- Conduct independent and collaborative research, under the supervision of Dr. Turner, focused on one or more of the five major challenges outlined in Precision Genomics.
- Develop and apply computational and/or experimental techniques to identify and interpret genomic variation.
- Analyze large-scale genomic and multi-omic datasets using custom and existing pipelines.
- Design and implement functional validation assays for candidate variants, genes, or regulatory elements.
- Present research findings at national and international conferences, and contribute to high-impact publications.
- Mentor graduate students and contribute to lab meetings and collaborative projects within the university and with external partners.
Other
- Ph.D., M.D. Or Equivalent Terminal Or Doctoral Degree. - Neuroscience
- At least two first-author publications in peer-reviewed journals.
- Strong publication record demonstrating independent research ability.
- Excellent communication skills and ability to work both independently and in a collaborative, multidisciplinary environment.
- This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.
