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Principal Applied Scientist

Microsoft

$139,900 - $304,200
Oct 2, 2025
Remote, US
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Microsoft is looking to drive innovation at the intersection of vibe coding, low code, and Copilot by developing AI-native business applications that enable multi-step reasoning and decision-making, empowering customers and partners to build on their platform.

Requirements

  • Prior expertise in natural language processing (NLP)
  • Strong foundation in large language model (LLM) development, evaluation, and fine-tuning
  • Experience in applying advanced fine-tuning techniques—including instruction tuning, reinforcement learning from human feedback (RLHF), and tool-augmented generation—to build agents capable of multi-step reasoning and decision-making
  • Familiarity with prompt engineering, context-aware orchestration, and integrating LLMs with external tools and APIs
  • Comfortable working in a experimentation-driven environment, leveraging both offline and online evaluation methods to iterate rapidly and optimize agent behavior
  • Deep understanding of the challenges and opportunities in building AI-native enterprise applications
  • 5+ years experience creating publications (e.g., patents, libraries, peer-reviewed academic papers)

Responsibilities

  • Lead rapid experimentation cycles
  • Develop robust evaluation frameworks
  • Apply advanced techniques like reinforcement learning to enable multi-step reasoning and decision-making
  • Collaborate across engineering, product, and partner teams to ensure agents are performant, secure, reliable, and extensible
  • Master a broad area or research and understand any applicable research techniques
  • Serve as a team expert on changes in industry trends, products, and other advances, and apply this knowledge to influence product needs
  • Incorporate research, and provide strategic direction for problem solving

Other

  • Ability to meet Microsoft, customer and/or government security screening requirements are required for this role.
  • Microsoft Cloud Background Check
  • 2+ years experience presenting at conferences or other events in the outside research/industry community as an invited speaker.
  • Bachelor's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 6+ years related experience (e.g., statistics, predictive analytics, research) OR Master's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 4+ years related experience (e.g., statistics, predictive analytics, research) OR Doctorate in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 3+ years related experience (e.g., statistics, predictive analytics, research) OR equivalent experience.
  • Microsoft will accept applications for the role until October 7, 2025.