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Principal Applied Scientist

Microsoft

$139,900 - $304,200
Jan 1, 2026
Redmond, WA, US
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Microsoft is looking to shape the future of the autonomous enterprise and lead the development of intelligent, agent-first experiences that transform how businesses operate

Requirements

  • Prior expertise in natural language processing (NLP), with a solid foundation in large language model (LLM) development, evaluation, and fine-tuning
  • Hands-on experience in applying advanced fine-tuning techniques—including instruction tuning, reinforcement learning from human feedback (RLHF), and tool-augmented generation—to build agents capable of multi-step reasoning and decision-making
  • Familiarity with prompt engineering, context-aware orchestration, and integrating LLMs with external tools and APIs
  • Experience developing and deploying AI/ML products or systems at multiple points in the product cycle from ideation to shipping
  • 5+ years experience creating publications (e.g., patents, libraries, peer-reviewed academic papers)
  • 2+ years experience presenting at conferences or other events in the outside research/industry community as an invited speaker
  • 5+ years experience conducting research as part of a research program (in academic or industry settings)

Responsibilities

  • Drive strategic impact by identifying and leading high-leverage data science and analytics initiatives across multiple product domains
  • Lead the development and deployment of advanced model fine-tuning pipelines, leveraging Reinforcement Learning from Human Feedback (RLHF) to align AI system behavior with human intent and improve performance in complex, real-world enterprise scenarios
  • Design and implement robust measurement systems, experimentation frameworks, and causal inference methodologies tailored to dynamic AI systems and enterprise-scale environments
  • Mentor and elevate the data science community by championing best practices, nurturing talent, and cultivating a collaborative, high-performance culture
  • Harness AI to accelerate workflows and amplify team productivity through intelligent automation and innovation
  • Steer strategic direction and investment decisions by owning complex, end-to-end projects that blend technical depth with organizational influence
  • Build alignment and trust across leadership and cross-functional teams through clear, persuasive communication and collaborative engagement

Other

  • Bachelor's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 6+ years related experience
  • Ability to meet Microsoft, customer and/or government security screening requirements
  • Microsoft Cloud Background Check: This position will be required to pass the Microsoft Cloud background check upon hire/transfer and every two years thereafter
  • Travel requirements not specified
  • Visa requirements not specified