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Principal Engineer: AI/ML Innovation- REMOTE

Thorne

Salary not specified
Dec 4, 2025
Remote, US
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At Thorne, the business and technical problem is to lead next-generation personalization and data-driven wellness initiatives by transforming early research models into production-grade AI and machine learning systems that deliver measurable value.

Requirements

  • Advanced Python skills, including FastAPI, async microservices, and ML infrastructure development.
  • Hands-on experience with AWS AI/ML services (Bedrock, ECS, Lambda, OpenSearch, CloudWatch).
  • Deep understanding of vector databases, retrieval architectures, and embedding pipelines.
  • Strong MLOps experience (CI/CD, model registry, reproducibility, automated deployment).
  • 7+ years of software or ML engineering experience, with 2+ years in production AI/ML deployment.
  • Experience with TensorFlow, PyTorch, Scikit-learn, or XGBoost.
  • Experience with OpenSearch, Bedrock, and other vector databases.

Responsibilities

  • Collaborates with Science, Data, and Product teams to prototype and validate AI/ML models using Python, FastAPI, and modern orchestration frameworks.
  • Leads efforts to productionize machine learning prototypes, ensuring scalability, reproducibility, and performance.
  • Designs and deploys ML pipelines and inference services using TensorFlow, PyTorch, Scikit-learn, or XGBoost.
  • Develops and optimizes agentic LLM pipelines, RAG workflows, and semantic search using OpenSearch, Bedrock, and other vector databases.
  • Partners closely with IT and DevOps to operationalize innovation in a secure and compliant manner.
  • Integrates LLM and generative AI APIs (OpenAI, Bedrock, Anthropic, etc.) into production systems.
  • Mentors junior engineers and data scientists on best practices in experimentation, deployment, and observability.

Other

  • This is a remote position.
  • Background in health tech, wellness, or regulated environments (DSHEA, HIPAA) is a plus
  • Develops and delivers on assigned objectives within requested timeframes.
  • Works cooperatively with executives and senior managers in other departments.
  • Possesses good interpersonal skills engages others in a positive manner.