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Principal GPU Software Engineer I

Roche

$142,500 - $264,700
Dec 5, 2025
Santa Clara, CA, US
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Roche Sequencing is developing ground-breaking next-generation sequencing products that allow scientists/clinicians powerful new avenues to investigate DNA, the blueprint of any lifeforms, in days, giving them the ability to understand health conditions such as cancer, HIV, COVID19 and more! We are not only changing science but changing lives through the development of frontier technologies that accelerate personalized healthcare. We are looking for a Principal GPU Software Engineer to develop GPU-accelerated software targeted for real-time primary analysis on a DNA sequencing instrument.

Requirements

  • You have experience with Object-oriented programming in C++ and experience with GPU-accelerated C/C++ libraries such as CUDA, Thrust, etc.
  • You have experience with recent C++ compiler standards (C++14/17) as well as algorithm frameworks (boost, thrust, TBB, etc.).
  • You have experience in writing, debugging and optimizing parallel (CPU and GPU) Linux applications.
  • You have experience in utilizing popular ML frameworks such as TensorFlow or PyTorch to develop and deploy machine learning models for predictive analytics and classification tasks.
  • You have working knowledge of QSR/cGMP, ISO and Design Controls
  • You have experience with Python and digital signal processing

Responsibilities

  • Work closely with research and algorithm experts, accelerating bioinformatics techniques using GPU hardware
  • Proficient in developing GPU-accelerated software in C/C++, with familiarity in Python for signal processing numerical analytics
  • Support software development lifecycle and Design Control process, working closely with team members to continuously improve quality and feature sets of the software products, based on technical design and requirements specifications
  • Produce well documented software along with test and validation to build high quality output
  • Establish best practices for software development methodologies and standards to ensure the highest quality of the software product delivered to users
  • Proactively work with engineering and research teams to ensure all technical aspects of software development are accurately communicated to all stakeholders

Other

  • You have a Bachelor's degree in Computer Science, Computer Engineering or related field plus 6 years of direct related experience; Master/PhD is a plus. Or, a combination of education and experience to perform at this level.
  • You have proven technical leadership skills to implement and integrate new technologies along with best practices.
  • Relocation benefits are not available for this position.