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Natera Logo

Principal ML Engineer

Natera

$178,900 - $223,650
Aug 28, 2025
Remote, US
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The company is looking to implement advanced AI models across clinical and genomics applications to drive real-world results in precision medicine.

Requirements

  • Proficiency in deep learning frameworks such as PyTorch, TensorFlow, or Keras
  • Experience with integrating LLMs into downstream clinical workflows
  • Expertise in fine-tuning and optimizing pre-trained models for domain-specific applications
  • Familiarity with agent frameworks and retrieval-augmented generation techniques
  • Experience with semantic search, hybrid search, and vector databases
  • Strong programming skills in Python
  • Experience with containerization and orchestration

Responsibilities

  • Identify and evaluate best-fit models for a wide range of tasks
  • Fine-tune or optimize foundation models for targeted clinical/genomic outcomes
  • Design for scalability, observability, and maintainability in ML deployments
  • Package and serve models for production inference
  • Build agentic systems that can answer complex clinical or genomic queries
  • Automate human-in-the-loop workflows for expert-level decision support
  • Own the ML engineering stack, from model integration and experimentation to cloud-native deployment

Other

  • PhD in Computer Science, Computational Biology, Bioinformatics, Statistics, or related field, or equivalent practical experience
  • 8+ years of experience applying machine learning to real-world problems
  • Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents