Gilead is seeking a Principal Scientist to support its growing Oncology targeted large molecule portfolio by identifying and validating novel targets, developing next-generation T cell engagers, and deepening the understanding of their mechanism of action and resistance mechanisms.
Requirements
- Ph.D. in Immunology, Oncology, Cell Biology or related field.
- 5+ years of relevant experience with PhD; 6+ Years relevant industry experience and with postdoctoral training preferred
- Demonstrated ability to design and execute in vitro and in vivo studies for Oncology and immuno-oncology.
- Proficiency in data analysis tools and statistical software; experience with AI/ML applications is a plus
- Deep expertise and understanding of Oncology and immune-oncology and the competitive landscape.
- Proven track record of publications and/or patents
- Exceptional problem-solving abilities and scientific judgment
Responsibilities
- identifying and validating novel targets for T cell Engagers
- developing next-generation approaches to make T cell engagers safer and more efficacious against solid tumors through engineering or novel combination approaches
- deepen our understanding of the mechanism of action of T cell engagers and resistance mechanisms through innovative pre-clinical model development and analysis
- Design and lead cross-functional therapeutic projects in the field of T cell engagers and enhancers of T cell functions, leveraging internal and external resources.
- lead from the bench and actively participate in the design and execution of critical experiments
- Support the development of Oncology portfolio at Gilead through project ideation and scientific experimentation.
- Manage reports and lead a productive research team dedicated to identifying and validating new targets for given cancer indications and developing new biologics platforms for optimal engagement and stimulation of T cells.
Other
- Minimum 3 years in a managerial role with demonstrated team management experience.
- Strong project management skills with ability to oversee multiple projects simultaneously while maintaining high quality standards.
- Excellent verbal and written communication skills with the ability to influence and collaborate effectively across disciplines and present to executive leadership.
- Bachelor's Degree and 10 years experience OR Master's Degree and 8 years experience OR PhD/PharmD and 2 years experience OR MD