Stoke Therapeutics is looking to solve the problem of restoring protein expression by harnessing the body’s potential with RNA medicine, specifically for diseases of the central nervous system and the eye caused by haploinsufficiency.
Requirements
- Strong background in cell and molecular biology research; understanding of the basics of PCR is a must.
- Strong hands-on experience in RNA isolation techniques from cells and tissues, mammalian cell culture and cell-based assays is strongly desirable.
- Experience with molecular and cell biology research, preferably in industry
- Understanding of the basics of PCR
- Experience with RNA isolation techniques from cells and tissues
- Experience with mammalian cell culture and cell-based assays
Responsibilities
- Work in aseptic conditions and maintain cultures of various cell types.
- Screen and evaluate ASOs in relevant mouse tissues and cell-based assays.
- Perform cell and molecular biology techniques such as RNA, DNA and protein isolation, RT-PCR, RT-qPCR, western blotting and other project-specific assays, as necessary.
- Troubleshoot experiments, analyze and interpret data, participate in development of new assays with support from more senior scientists.
- Maintain accurate documentation of experiments in electronic lab notebook (ELN).
- Present research findings at group meetings.
Other
- BS with 2 years of post-graduate experience in molecular and cell biology research, preferably in industry or a Master’s degree in molecular or cellular biology.
- Strong organizational and recordkeeping skills is a must.
- Ability to adapt to changing priorities and deadlines.
- Excellent planning and time management skills including the ability to support and prioritize multiple projects.
- Approximately 5% travel required
