The Chan Zuckerberg Biohub San Francisco (CZ Biohub SF) is initiating a comparative virology project to understand how cellular wiring and remodeling occur in health and disease through phenotypic and multiomic measurements of cells subjected to perturbations like viral infections or gene knock-outs. This involves integrating molecular biology, cell line engineering, imaging, transcriptomics, proteomics, and data science to generate large datasets for biological insights.
Requirements
- Experience with transcriptomics and sequencing library preparations
- Experience with microscopy, immunofluorescence and in situ hybridization
- Programming experience with Python and R
- At least 2 years of molecular biology experience in a research laboratory setting
Responsibilities
- Learn and implement cutting edge techniques including bulk, single cell, and spatial transcriptomics, CRISPR, and next generation sequencing under the mentorship and supervision of senior researchers.
- Perform basic molecular biology (nucleic acid isolation, PCR)
- Learn to automate protocols and utilize liquid handlers.
- Collaborate with personnel from different technology platforms (proteomics, computational microscopy, bioengineering, computational biology) and research groups (cell biology, zebrafish development, infectomics, virology).
- Troubleshoot protocols, develop clear experimental pipelines, maintain detailed records, analyze results, and contribute ideas to research projects
Other
- Passion for research
- Enthusiasm for cross-team collaboration and open science
- Team-oriented mindset
- Experience and excellence in documenting experiments
- Excellent written and oral communication skills
