Freenome is seeking a Research Associate II to develop and validate clinical-grade assays for measuring complex, blood-based analytes, aiming to advance cancer diagnostics and change the landscape of cancer detection.
Requirements
- Hands-on experience in NGS based assay development including sample preparation, library preparation, target capture, and sequencing
- Experience with automated platforms in plate-based, low-volume formats and/or microfluidics and experience working with automated liquid handlers
- Biological understanding of human cell-free nucleic acids and/or cancer biology
- Ability to manual pipette with high confidence, accuracy, and precision
- Experience working in a regulated laboratory environment (CLIA, GLP/GCLP, IVD development)
- Experience using ELN (electronic lab notebook) and LIMS (lab information management system)
- Familiarity with programing in a scientific programming language (e.g., Python or R)
Responsibilities
- Apply knowledge of molecular biology, nucleic-acid biochemistry, and next-generation sequencing to develop assays for DNA, including genome-wide and targeted approaches
- Characterize automated assays by generating and analyzing experimental data
- Create and manipulate high impact assay inputs, including samples and reagents formulation as required
- Gather high-quality data, take detailed notes, and openly communicate on lessons learned while performing experiments
- Collaborate with development team and computational biologists, analyze data and generate study conclusions
- Collaborate with clinical laboratory members to transition development protocols into production, including automation, validation experiments, and SOP development
- Present data in cross functional teams
Other
- Bachelors with 2+ years of relevant industry experience or Masters in molecular biology, or a related field
- High attention to detail and ability to record accurate and detailed observations, assess impact, and perform troubleshooting as required
- Flexible and highly motivated to learn new skills and comfortable adapting to changing priorities
- Clear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplines
- This role will be an onsite role based in our Brisbane, California headquarters.
