Freenome is seeking a Research Associate II to optimize next-generation sequencing (NGS) processes and develop new methodologies on their multiomics platform to contribute to developing life-saving diagnostics through early cancer detection.
Requirements
- Hands-on experience in NGS based techniques, including nucleic acid extraction, library preparation, and sequencing
- Experience with handling plasma and cfDNA in NGS workflows with low-volume, plate-based assay formats
- Familiarity in a common scientific programming language (e.g., Python, R) is desirable
Responsibilities
- Apply hands-on knowledge of molecular biology, nucleic-acid biochemistry and next generation sequencing to develop and optimize NGS based methods and processes
- Execute experiments to characterize and optimize NGS workflows, converting prototypes into high-throughput automated assays
- Participate in data analysis and visualizations to answer experimental questions and identify areas for workflow optimization
- Present findings at team meetings and prepare technical reports for internal and external stakeholders
- Collaborate with cross-functional teams to integrate process improvements into the overall diagnostic workflow
- Assist with generating Standard Operating Procedures and Work Instructions with Laboratory Operations and Clinical Laboratory for transfer
- Support troubleshooting workflow issues, perform root-cause determinant experiments and propose effective data-driven solutions
Other
- The role reports to the Senior Manager of Genomics Early Development.
- This role will be an onsite role based in our Brisbane, California headquarters.
- Effectively communicates with team and cross-functional partners
- High attention to detail - record and document accurate, objective observations, assess impact, and perform troubleshooting as needed
- Excellent problem-solving skills, proactively looks for potential roadblocks, characterizes root causes to problems and collaborates with appropriate stakeholders
- Ability to work independently as well as part of a cross-functional team
- Flexible and adaptable to change and embrace a fluid work environment
