The R&D team at Twist is looking to develop new products and applications in the Next-Generation Sequencing (NGS) space by leveraging their silicon-based, massively-parallel DNA synthesis platform.
Requirements
- Must have strong background in molecular biology techniques and hands-on experience with methods for manipulating and analyzing nucleic acids (e.g. DNA/RNA extraction, purification and quantification, PCR, enzymatic assays, hybridization and primer design)
- Hands-on experience with NGS and NGS applications (e.g. library preparation, target enrichment, sequencing and sequencing data analysis)
- Bioinformatics and programming skills (python, R, shell scripting)
- Experience with liquid handling systems and automation tools
- Fundamental background in dPCR, ddPCR or qPCR is preferred
- Familiarity and/or interest in either liquid biopsy and/or LIMS system a plus.
Responsibilities
- Design and perform experiments in collaboration with scientists and bioinformaticians, under aggressive timelines
- Evaluate, optimize and troubleshoot NGS-based workflows and assays to improve performance
- Document experimental designs and results; keep excellent records and data
- Analyze experimental data to provide recommendations for the next experimental steps
- Present and communicate experimental results to multidisciplinary team members
- Support the larger R&D team in various lab/day-to-day operations and activities across the board
Other
- S. with 2-3 years or M.S. with 1-2 years of experience in Molecular Biology, Biochemistry, Chemistry or a closely-related field
- High attention to detail. Ability to identify problems and use a combination of knowledge, intuition, and experience to solve problems in a timely manner
- Self-motivated and passionate about your work
- Excellent interdisciplinary communication skills required
- Willing and able to grow with a fast-paced, highly-collaborative, multidisciplinary team
