Character Biosciences is a precision medicine company focused on developing targeted therapies for polygenic diseases, specifically in ophthalmology. The company aims to uncover genetic drivers of disease progression, advance novel therapeutics, and define patient stratification strategies to improve clinical success by integrating genomics with clinical and imaging data.
Requirements
- hands-on experience with mammalian cell culture, assay development, ELISA, and fluorescent microscopy.
- Experience with iPSC-derived neurons and glia is highly desirable.
- high-content cell imaging
- ELISA
- qPCR
- immunoblotting
- immunohistochemistry and flow cytometry.
Responsibilities
- Engineer, maintain, and differentiate iPSC-derived and/or primary human neurons and glia for disease modeling
- Develop and perform cell-based functional assays and in vitro assays, including but not limited to high-content cell imaging, ELISA, qPCR, immunoblotting, immunohistochemistry and flow cytometry.
- Independently plan, execute and troubleshoot experiments and collaborate effectively with team members to solve problems
- Coordinate tasks across multiple projects and keep meticulous records
- Organize, analyze and communicate results in team meetings
Other
- BS with 3+ years (or MS with 1+ years) of research experience in neurobiology, stem cell biology or related discipline.
- Must be nimble and able to work with changing priorities.
- Ability to work independently and collaboratively.
- Must have excellent troubleshooting, organizational and communication skills.
- on-site laboratory position located at Brisbane, CA.
