Septerna is looking to develop life-changing medicines for patients with unmet needs by becoming the industry-leading G protein-coupled receptor (GPCR)-focused drug discovery company.
Requirements
BSc or MSc in Pharmacology, Toxicology, or related biological science
2- 4 years of direct full-time hands-on experience with in vivo studies or disease models in academia or the biotechnology and pharmaceutical industries
Demonstrated ability to be hands on and work directly with rodent models (mice and rats), including multiple routes of administration (e.g. oral, subcutaneous, intraperitoneal, intravenous, intramuscular) and sample collection (e.g. submandibular bleed, tail vein bleed, cardiac puncture, etc).
Experience working with other scientists to analyze, interpret, and present data
Ability to collaborate in writing protocols and trouble-shooting biological experiments
Experience working with protein and RNA/DNA (e.g. ELISA, qPCR)
Experience working with primary cells or ex vivo models or in vivo species
Responsibilities
Design and execute in vivo pharmacology studies to understand therapeutic mechanism in relevant disease models
Generate, analyze, document, and help interpret data to establish functional PK/PD relationships
Work collaboratively to determine the mechanism of action of drug candidates in in vivo, in vitro and ex vivo models
Perform in literature searches, read and interpret papers to help design and trouble-shoot in vivo and in vitro experiments
Help in authoring in vivo pharmacology study designs, protocols, and reports to support regulatory filings
Follow all company policies/practices, and maintain accurate records and notebooks
Be a member of multiple project teams and present results in lab, team and department meetings
Other
Detail-oriented and organized, with strong interpersonal skills for clear and effective communication – ability to proactively engage and collaboration with colleagues
BSc or MSc degree
2- 4 years of experience
Ability to work in a fast-paced environment
Ability to work collaboratively in an inter-disciplinary setting
