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Research Chemist

Spark Climate Solutions

Salary not specified
Sep 5, 2025
Watertown, MA, US
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Protein dysfunctions directly cause many diseases, such as Alzheimer’s disease. Yet, proteins remain understudied because of technological hurdles. Parallel Squared Technology Institute (PTI) aims to catalyze a leap in protein analysis technology and use it to explore new biological frontiers.

Requirements

  • Experience in optimizing organic chemistry reaction conditions
  • Experience with mass spectrometry (LC-MS) analysis of small molecules, peptides or proteins
  • Experience in synthesizing small molecules for protein modification
  • Strong foundation in diverse synthetic transformations and reaction strategies

Responsibilities

  • Discover and optimize new labeling chemistries for covalent modification of proteins and peptides
  • Develop and optimize sample clean-up approaches
  • Define new directions for technology development that can unlock new testable hypotheses
  • Prepare internal reports and manuscripts as well as present results at internal or external scientific meetings as appropriate

Other

  • 5+ years of experience in medicinal chemistry in a professional setting OR PhD in Chemistry or Chemical Biology or related field
  • Mentor scientists and research associates
  • Demonstrate a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others
  • Highly motivated and organized researcher with strong analytical skills
  • In order to be seriously considered for this position, we require a cover letter as part of the candidate’s application.