Iambic Therapeutics is seeking a Research Scientist to apply advanced ML techniques to drive their drug discovery efforts, working on hit identification, lead optimization, and candidate selection phases.
Requirements
- Python programming
- statistics
- drug discovery
- Experience with molecular modeling/structure-based drug design and cheminformatics
Responsibilities
- Design, train, evaluate and deploy ML models for predicting drug-target interactions and molecular properties
- Apply ML models to the prioritization of virtual molecules: including de novo design ideas, HTE libraries and commercial collections
- Partner with computational chemists, medicinal chemists and biologists to leverage ML insights for decision-making
- Serve as a bridge between the bench and our computational platforms
- Translate scientific questions into computational workflows and deliver actionable results
- Present results to project teams and senior leadership, explaining methods, implications and recommendations
- Collaborate with ML group to optimize model performance and evolve platforms
Other
- PhD or equivalent degree in a computational field, or commensurate job experience
- Able to locate in San Diego
- 2+ years of experience working in a drug discovery project
