The Biologics Research Center (BRC) at Novartis is looking to advance its diverse programs in the biologics pipeline and accelerate the discovery process by hiring a Research Scientist II to support protein engineering functions.
Requirements
- Knowledge with recombinant protein expression techniques.
- Experience in mammalian cells or bacterial expression system is preferred
- Knowledge with affinity and SEC protein purification techniques are required.
- IEX and HIC are plus.
- Knowledge with basic protein characterization techniques, such as protein concentration measurement, SDS-PAGE and Western blot.
- Experience in using molecular biology techniques and software, such as SnapGene for construct design and DNA sequence analysis is a plus
- Experience with antibody is highly desirable.
Responsibilities
- Conduct protein expression, purification and characterization; May need to design constructs.
- Perform routine cell-based assays for engineered biologics candidates screening.
- Implement experimental steps and existing lab techniques according to established laboratory protocols with input from senior lab members or manager.
- Summarize of raw data, report experimental details, and provide basic data analysis.
- Present data and findings in internal project meetings.
- Maintain excellent notebook record and comply company documentation compliance.
- Support senior lab members in the lab to contribute to pipeline and exploratory projects.
Other
- Bachelors degree in biochemistry, molecular biology or related degree with at least 1 year of post educational experience in academia or industry OR Masters degree with experience in academia or industry.
- Excellent team player with collaboration, communication, and interpersonal skills to work with cross functional teams
- Is curious about the drug discovery process with an eager to learn attitude.
- Detailed orientated and well organized.