The Ohio State University's Radiation Oncology department is seeking a researcher to investigate DNA replication fork stalling, DNA repair pathways, and mechanisms of resistance to cancer therapies.
Requirements
- Hands-on experience in molecular and cellular biology techniques (e.g., CRISPR/Cas9, Western blotting, immunofluorescence, DNA repair assays).
- Strong background or demonstrated skills in bioinformatics analysis of large datasets.
- Familiarity with DNA repair and replication biology is highly desirable.
- Experience with cancer biology or therapeutic resistance models.
- Proficiency in programming languages commonly used for bioinformatics (e.g., R, Python).
- Prior publication or contributions to scientific research projects.
Responsibilities
- Conduct molecular and cellular biology experiments, including cell culture, gene editing, protein/DNA analysis, and functional assays related to DNA replication and repair.
- Perform bioinformatics analyses of genomic, transcriptomic, and proteomic datasets to support experimental findings and generate new hypotheses.
- Collaborate with team members to design, execute, and troubleshoot experiments.
- Maintain accurate records of research activities and prepare data for presentations, reports, and publications.
- Assist in training and mentoring junior lab members as needed.
- Ensure compliance with laboratory safety protocols and institutional regulations.
Other
- Master’s degree in molecular biology, cell biology, bioinformatics, biochemistry, or a related field; PhD degree preferred.
- 3 years of relevant experience required with Bachelor's Degree, or 1 year of relevant experience required with Master's Degree.
- Excellent organizational, communication, and teamwork skills.
- Ability to work independently and manage multiple projects simultaneously.
- Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.
