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Senior Backend Engineer, AI Sim

SandboxAQ

$154,000 - $216,000
Aug 27, 2025
Remote, US
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SandboxAQ is seeking a backend engineer generalist to contribute to their drug discovery and chemistry simulation platform, aiming to solve challenges in life sciences and chemistry simulation.

Requirements

  • 3+ years of experience with Python with knowledge of software design principles and architectural patterns.
  • Comfort writing clean, readable, well-tested, maintainable code.
  • Experience with at least one major cloud provider. GCP preferred.
  • Experience with building REST APIs and knowledge of best practices.
  • Knowledge of cloud orchestration technologies like K8s or batch-type systems as well as workflow management tools (Airflow or similar)
  • Knowledge of database systems and related concepts: ORMs, schemas, and transactional vs. analytic systems.
  • Exposure to Terraform or another IaC system, along with DevOps and GitOps.
  • Knowledge of CI/CD best practices and building CI/CD pipelines.

Responsibilities

  • Contribute to the development of SandboxAQ’s chemistry and life sciences simulation platform.
  • Work closely with users and members of the product team to measure the impact of the code you develop on users, gather feedback, and iterate on your software.
  • Participate in planning, design, and sprint ceremony meetings.
  • Embed closely with R&D teams to assist in delivering project goals and drive adoption of practices and tooling.
  • Collaborate closely with the product team and internal stakeholders in all phases of software development to validate the solutions you propose and implement.
  • In collaboration with the rest of the engineering team, build and manage infrastructure for SandboxAQ’s simulation and data platform.
  • Review code and participate in design and architectural discussions.

Other

  • Excellent communication and collaboration skills, with the ability to effectively influence a cross-functional team.
  • You’re entrepreneurial and customer-obsessed.
  • Most importantly, you’ll bring a track record of working in a fast-moving software development team, exploring new technologies, and solving problems across an entire software stack.
  • Domain experience in advanced materials, drug discovery, cheminformatics, or other areas of chemistry or biology, especially experience with AI systems applied to these domains.
  • Delivering scientific code for R&D projects, especially in the simulation and numerical optimization domains