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Senior Backend Software Engineer, Agentic AI

SandboxAQ

$154,000 - $256,000
Aug 14, 2025
Remote, US
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SandboxAQ is seeking a founding backend engineer to build the core of their Agentic AI platform, which aims to solve real-world problems in drug design, materials science, and chemistry at scale by enabling autonomous systems to interact with the physical world.

Requirements

  • 5+ years of experience with Python, with strong knowledge of software design principles.
  • Understanding of database principles and best practices.
  • Experience with writing and optimizing database queries, graph database experience is a plus.
  • Strong understanding of web and network fundamentals and experience with designing, building, and testing web APIs.
  • Knowledge of CI/CD best practices and building CI/CD pipelines.
  • 3+ years of fluency in infrastructure as code (Terraform), and containerized deployments on public cloud providers. GCP preferred.
  • Comfort with agentic frameworks, orchestration tools (LangGraph, Haystack, CrewAI, OpenAI Function Calling, etc.), or custom agent architectures is highly desirable.

Responsibilities

  • Design and own the architecture of intelligent agents that autonomously coordinate and drive complex scientific pipelines.
  • Develop multi-agent orchestration frameworks and autonomous workflows for simulation and modeling under the guidance of a Tech Lead.
  • Design, implement, and scale agentic systems—including autonomous, goal-driven agents and multi-agent workflows—to enable users to configure, monitor, and scale large chemical simulations and scientific pipelines.
  • Build scalable, production-ready APIs and data systems that interact with simulations, ML models, external APIs, and other agents.
  • Integrate observability, traceability, and performance analytics into everything you build.
  • Contribute to the design and implementation of complex, security-sensitive data processing and storage systems with complex tenancy and data isolation requirements.
  • In collaboration with the rest of the engineering team, build and manage infrastructure for SandboxAQ’s simulation and data platform.

Other

  • Strong interest in agentic AI, autonomous agents, and multi-agent system design.
  • Experience with building frontends for web applications.
  • You care deeply about developer experience; clean code, clear APIs, and great internal tools.
  • Excellent communication and collaboration skills, with the ability to effectively influence a cross-functional team.