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St. Jude Children's Research Hospital Logo

Senior Bioinformatics Research Scientist

St. Jude Children's Research Hospital

$104,000 - $186,160
Sep 14, 2025
Memphis, TN, US
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St. Jude is seeking to solve the problem of electronic health record (EHR)-driven phenotyping to support pharmacogenomics discovery research within the Center for Pharmacogenomics in the Department of Pharmacy and Pharmaceutical Sciences.

Requirements

  • Significant experience in at least one programming or scripting language and at least one statistical package, with R preferred.
  • Demonstrated expertise in EHR-based phenotype extraction and curation are strongly preferred.
  • Experience with large external biobank datasets such as All of US, eMERGE, TopMed, UK BioBank, as well internal EHR data.
  • Experience with terminology/ontology, natural language processing, and machine learning.
  • Experience with bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry).
  • Experience with data analysis and statistical packages.
  • Experience with programming languages such as R.

Responsibilities

  • Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data.
  • Deliver data files, and document the analytical process. May participate in manuscript preparation at project's conclusion.
  • Assist with establishing and documenting protocols or best practices for common research tasks, and in the formulation of analytical plans that use the best approach to address challenging data analysis questions.
  • Assist in the evaluation and testing of new methods and technologies.
  • Contribute ideas to automate or improve existing analysis methods. Implement the improvement or work with others to do so.
  • Participate in the department's developmental projects and interdepartmental team projects.
  • Develop and implement new informatics tools and resources to enhance phenotyping performance or enable deep phenotyping through terminology/ontology, natural language processing, and machine learning.

Other

  • Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work experience in relevant area (e.g., bioinformatics, cheminformatics, statistics/computer science with a background in biological sciences or chemistry) (OR) Master's degree with 5+ years of relevant experience (OR) PhD with 2+ years of relevant experience.
  • Maintains regular and predictable attendance.
  • Provide research support and deliver high-quality results by formulating an efficient analytical approach with the available data.
  • Perform other duties as assigned to meet the goals and objectives of the department and institution.
  • Explore our exceptional benefits!