Axsome Therapeutics is seeking a Senior Director, Health Economics and Outcomes Research (HEOR) to provide strategic leadership for the value proposition of their products and pipeline assets, addressing critical gaps in central nervous system (CNS) condition treatments.
Requirements
- Experience in design, conduct and oversight of real-world evidence studies ranging from protocol writing to project management oversight and data interpretation and communication
- Ability to explain strengths and limitations of clinical practice datasets — such as electronic health records, claims, clinical data registries, patient generated health data, and other health data sources — in context of designing observational study designs
- Demonstrated depth of understanding of observational research methods, regulatory standards, and ability to leverage epidemiologic and data science expertise to meet evolving business needs
- Solid understanding of the cross functional drug development lifecycle and processes (business development, clinical trial design, conduct, & endpoint selection, biostatistics, and regulatory)
- Ability to impact, influence, and interact with senior business leaders and partners.
- Experience and awareness of Reimbursement and Access environments
- Demonstrable success in employing innovative techniques to overcome data limitations
Responsibilities
- Shape and influence the strategic execution of observational research to inform a variety of stakeholders including clinicians, payers, policy makers, patient groups, as well as internal decision making.
- Conceptualization and execution of scientifically credible research on Axsome assets and their disease states / therapeutic areas, guided by the development of a strategic evidence generation plan.
- Provide HEOR, epidemiologic, patient-reported outcomes, or/and RWE expertise and support to medical teams, brand teams, & program teams, and disseminate technical information through technical reports, presentation, and publication in peer-reviewed literature as agreed by the team.
- Contribute to the design, HEOR endpoint selection, reporting and analysis of clinical studies including subgroup analyses.
- Lead and create global value and AMCP dossiers.
- Perform critical assessments & analyses of medical and scientific evidence including systematic reviews, RWE, economic evaluations as the basis for HTA assessments, disease management guidelines, and formulary evaluations.
- Develop cost-effectiveness model-based economic evaluations, budget impact analyses, cost-offset analyses and burden of illness studies.
Other
- Reporting to the Associate Vice President, HEOR
- This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week.
- We are unable to consider candidates who are looking for fully remote roles.
- Excellent communication skills, advanced multi-stakeholder experience, and a highly-evolved capability to translate RWE strategic narratives to diverse audiences
- Effectively manage internal and external stakeholder expectations regarding strategic objectives and execution of research
