Axle is seeking a Senior Full Stack Engineer to build and maintain the foundational infrastructure of the National Clinical Cohort Collaborative (N3C), the nation's largest public repository of harmonized electronic health record (EHR) data, by developing a sophisticated, secure, and data-intensive web application ecosystem for researchers, administrators, and federal partners.
Requirements
- Expert-level proficiency with a modern backend framework (e.g., Python-based like FastAPI or Node.js-based like NestJS).
- Expert-level proficiency with a modern, component-based frontend framework (e.g., Angular, React, Vue, or Svelte).
- Demonstrable experience building, scaling, and maintaining complex, secure web applications, especially those handling user authentication/authorization, multi-tenancy, and complex workflows.
- Strong experience with SQL databases (e.g., PostgreSQL) and designing data models for application state and logging.
- Deep knowledge of the full SDLC, including CI/CD pipelines, containerization (Docker), container orchestration (Kubernetes), and Git.
- Experience in the healthcare, life sciences, or clinical research domain.
- Familiarity with health data standards (e.g., OMOP, FHIR) and interoperability challenges.
Responsibilities
- Own the complete design, development, and deployment of the DAME, the Phenotype Builder, and all associated web platforms.
- Engineer a robust, API-driven backend to manage complex business logic, including user authentication, authorization, multi-tenant permissions, and intricate data access workflows.
- Create a modern, responsive, and state-of-the-art user interface for all applications, focusing on UI/UX best practices to make complex data and workflows understandable and easy to manage.
- Design the Phenotype Builder to interact with large-scale aggregate data, providing researchers with near-real-time feedback while maintaining strict privacy controls.
- Drive development using Agile sprint cycles, implement comprehensive automated testing, manage deployments through CI/CD pipelines across all environments, and own all four pillars of production maintenance (corrective, adaptive, perfective, and preventative).
- Work with platform vendors to define and test requirements for core "Dynamic Workspace" infrastructure, and manage core application databases for master lists of agreements, IRBs, and sites.
Other
- A passion for building high-quality, user-facing applications that solve complex, meaningful problems.
- Bachelor's or Master's degree in Computer Science or a related field, with 8+ years of professional full-stack development experience.
- Direct experience with OHDSI tools (especially Atlas) or building other cohort exploration or phenotype-building applications.
- Experience designing and building applications for a multi-tenant, cloud-native environment (AWS, GCP, Azure).
- A strong understanding of UI/UX design principles and a portfolio of intuitive applications.
