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Tahoe Therapeutics Logo

Senior Machine Learning Engineer

Tahoe Therapeutics

Salary not specified
Dec 2, 2025
South San Francisco, CA, US
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Tahoe Therapeutics is looking to solve bottlenecks in drug discovery by building the world's largest in vivo single-cell perturbation atlas and using it to train multimodal foundation models. The company aims to find better drugs faster by combining cutting-edge machine learning with biologically relevant datasets.

Requirements

  • Solid Engineering and Computer Science fundamentals, ideally with a degree in CS, Math, or equivalent experience.
  • Exceptional engineering skills to iterate quickly on data processing and training pipelines
  • Experience in building, testing, training, and deploying modern neural network architectures such as Transformers.
  • Experience with frameworks like PyTorch, Tensorflow, Keras, JAX and the ability to write hardware optimized code for distributed training
  • Experience with distributed deep learning using frameworks such as HF Accelerate, Deepspeed, Composer, TorchTitan, Megatron etc.
  • Experience with training large neural networks on multiple compute nodes.

Responsibilities

  • Stay at the forefront of ML and computational biology research and rapidly adopt state-of-the-art techniques to train AI virtual cell models on our massive single cell datasets.
  • Work together with ML Scientists to develop the next generation of compute optimized models like Tahoe-x1.

Other

  • This position requires on-site presence at our South San Francisco office a minimum of three days per week.
  • We welcome applicants who require visa sponsorship and provide work authorization support for qualified candidates.
  • Unlimited Paid Time Off (PTO).
  • Monthly Lunch budget
  • One-time Office set up budget