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BeOne Medicines Logo

Senior Manager, AI Engineer

BeOne Medicines

$150,900 - $195,900
Sep 26, 2025
Remote, US
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BeOne is seeking an accomplished Senior Manager AI Engineering to provide technical leadership for a team of AI and machine learning engineers driving the next generation of AI solutions. In this pivotal role, you will contribute to the shape and execution of the R&D organization’s AI strategy, including the end-to-end development of robust, scalable models and platforms. Your expertise will ensure the successful deployment of cutting-edge AI technologies while fostering a strong, data-driven culture of innovation and excellence.

Requirements

  • 5+ years of progressive AI/ML engineering experience, including driving large-scale AI initiatives and collaboration with diverse high-performing engineering teams.
  • Proven success delivering production-grade, scalable AI/ML solutions that create measurable scientific or business impact.
  • Deep, hands-on experience in training, fine-tuning, hosting, and deploying large-scale generative models, with mastery of PyTorch (preferred) or TensorFlow for model development and optimization.
  • Demonstrated expertise in Agentic AI design and orchestration, leveraging frameworks such as LangGraph, LangChain, or similar to build intelligent, multi-step reasoning agents.
  • Strong capability in context engineering, prompt engineering, agent- or graph-augmented retrieval (Agent/Graph RAG), text-to-SQL generation, and multimodal AI (integrating text, image, structured data, etc.) to enable complex knowledge-driven applications.
  • Robust knowledge of MLOps best practices, including CI/CD pipelines for machine learning, model versioning, automated testing, scalable deployment, and cloud platforms (AWS, Azure, GCP).
  • We prefer familiarity with biomedical and pharmaceutical NLP technologies such as cTAKES, BioGPT, PubMed-based LLMs, or similar biomedical AI frameworks.

Responsibilities

  • Lead AI Development – Take the technical leadership of the design, build, and deployment of advanced AI/ML solutions aligned with business and scientific goals.
  • Collaborate Broadly – Partner with engineers, data scientists, and product teams to integrate models into production workflows.
  • Set Standards – Promote best practices for development, testing, deployment, and ongoing model performance.
  • Drive Innovation – Track emerging AI technologies and introduce new tools to keep the team at the forefront.
  • Ensure Compliance – Maintain strict data privacy, security, and ethical standards.
  • Deep, hands-on experience in training, fine-tuning, hosting, and deploying large-scale generative models, with mastery of PyTorch (preferred) or TensorFlow for model development and optimization.
  • Demonstrated expertise in Agentic AI design and orchestration, leveraging frameworks such as LangGraph, LangChain, or similar to build intelligent, multi-step reasoning agents.

Other

  • Exceptional ability to Lead and partner with cross-functional technical teams, mentor other engineers, and drive alignment with scientists, product leaders, and business stakeholders.
  • Superior communication skills for conveying complex AI concepts to diverse audiences, including research, regulatory teams.
  • Deep appreciation of data privacy, security best practices, and ethical considerations in AI development and deployment.
  • Bachelor’s or Master’s degree in Computer Science, Artificial Intelligence, Data Science, Engineering, or a closely related technical field (Ph.D. preferred).
  • When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.