DELFI Diagnostics is developing next-generation, blood-based tests that are reliable, accessible, and deliver a new way to help detect cancer. Employing advanced machine-learning methods to whole-genome sequencing data, the DELFI ("DNA EvaLuation of Fragments for early Interception") platform is built to address the highest-burden health challenges.
Requirements
- Proficient in high-throughput manual laboratory techniques, including precision pipetting for large-scale sample processing
- Proven track record in laboratory method optimization with specialized expertise in addressing technical challenges specific to nucleic acid extraction and library preparation for NGS.
- Strong analytical skills with demonstrated ability to independently design experiments and interpret results using sound scientific reasoning
- Excellent technical writing capabilities for developing experimental protocols, standard operating procedures, and comprehensive development reports
- Hands-on experience with automated liquid handling systems for assay development and execution
- Advanced data analysis skills using Excel and statistical software packages; programming experience in Python, R or similar languages is highly valued
- Direct experience in a regulated environment (CLIA, CAP, NYS, FDA, GXP, etc.)
Responsibilities
- Design, execute, and troubleshoot moderate to complex laboratory experiments utilizing molecular biology techniques for Next-Generation Sequencing (NGS).
- Perform end-to-end experimental workflows, including nucleic acid extraction, library preparation, and sequencing, while preparing samples and executing experiments with meticulous attention to detail and adherence to high-quality standards.
- Develop robust assay workflows by performing guard banding studies and verifying product requirements with analytical characterization studies.
- Communicate findings effectively with multidisciplinary teams, including biologists, bioinformaticians, statisticians, automation engineers, and quality control scientists, and present at scientific meetings.
- Contribute to advancing assays through design control processes to meet product requirements and regulatory standards by maintaining comprehensive documentation.
Other
- BS with 3-4 years of experience, or MS with 2-3 years relevant field (e.g., biomedical engineering, molecular biology, genetics, or genomics) in assay development for the life science industry
- Superior organizational and project management abilities, including meticulous documentation practices, strategic planning, and effective time management with keen attention to detail
- Proven track record of organization and cross-functional communication for study preparation and execution
- We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
