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Senior Research Associate, CMC

Pioneering Intelligence

$81,000 - $107,250
Oct 17, 2025
Cambridge, MA, US
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FL 87 is developing a novel approach to gene therapy to address currently untreatable diseases. The company is seeking to advance its platform by producing and characterizing nucleic acid therapeutics and establishing manufacturing scale-up capabilities.

Requirements

  • Synthesize and purify routine nucleic acid products for preclinical studies.
  • Operate and maintain lab instruments such as Fast Protein Liquid Chromatography (AKTA) system, Tangential Flow Filtration (TFF) system, biosafety cabinets (BSC), nanodrop, pH meters, and incubators.
  • Experience in preparing buffers for purification.
  • Assist in establishing and optimizing nucleic acid manufacturing scale-up capabilities.
  • Perform routine analytical and bioanalytical tasks such as HPLC, fragment analysis, UV, and fluorescence.
  • Ability to analyze, summarize, and communicate scientific data.

Responsibilities

  • Synthesize and purify routine nucleic acid products for preclinical studies.
  • Operate and maintain lab instruments such as Fast Protein Liquid Chromatography (AKTA) system, Tangential Flow Filtration (TFF) system, biosafety cabinets (BSC), nanodrop, pH meters, and incubators.
  • Experience in preparing buffers for purification.
  • Assist in establishing and optimizing nucleic acid manufacturing scale-up capabilities.
  • Perform routine analytical and bioanalytical tasks such as HPLC, fragment analysis, UV, and fluorescence.
  • Maintain up-to-date records and communicate results with team members through written technical reports and oral presentations.
  • Interpret, summarize experimental data, and keep detailed laboratory notebooks.

Other

  • BS with 1-5 years, MS with 1-3 years of academic or industry experience in nucleic acid manufacturing.
  • Attention to detail, multitasking ability, and troubleshooting skills.
  • Excellent written and verbal communication skills.
  • Strong record-keeping and data management skills.
  • The ideal candidate is adaptable, eager for new challenges, naturally curious, and passionate about learning.