Altos Labs is looking to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and disabilities, and the Senior Research Associate will support the development of innovative genomics workflows and integration of novel genomics pipelines.
Requirements
- In-depth, hands-on experience with NGS library preparation and QC, and an excellent understanding of the underlying biochemistry
- Strong hands-on experience with other standard Molecular Biology techniques (i.e. nucleic acid extraction and QC, PCR/qPCR, primer design, etc.)
- Experience with reagent validation, protocol optimization, and troubleshooting
- Knowledge and hands-on experience with operating and troubleshooting sequencing platforms including MiSeq, NextSeq, and Oxford Nanopore sequencers
- Hands-on experience with bulk, single-cell, and single-nuclei assays
- Experience with automation platforms is a plus
- Experience and/or familiarity with the application of spatial genomics technologies is a plus
Responsibilities
- Ownership of NGS project workflows from sample intake, RNA/DNA extraction and QC, NGS library preparation and QC, loading sequencing libraries onto Illumina/Nanopore sequencers, and assessing data quality after sequencing
- Provide daily operational support for genomics instrumentation and service pipelines
- Assist with planning future expansions with genomics workflow infrastructure, instrumentation and assay pipelines
- Develop, optimize, implement, and standardize state-of-the-art genomics pipelines
- Maintain accurate and detailed digital records including electronic lab notebook entries
- Broadly support the Genomics Hub operations, including reagent/consumable purchasing, management and maintenance of equipment and instruments
- Provide excellent communication of current workflows and hub capabilities
Other
- Bachelor’s or Master’s degree in Molecular Biology, Biochemistry, Genetics, Biotechnology, or a related field
- Minimum 5+ years of professional laboratory experience
- Excellent organizational skills, meticulous attention to detail, and record-keeping, particularly in electronic lab notebooks (ELNs)
- Excellent oral and written communication skills
- Ability to use technical skills and effective time management to perform work efficiently and meet project timelines
