Arc Institute is looking to scale its genomic sequencing capabilities to meet growing internal demand and enable breakthrough research by integrating and optimizing new sequencing platforms.
Requirements
- Hands-on experience with basic molecular biology and QC techniques including nucleic acid extraction, purification and quantification (using Bioanalyzer, Tapestation and Qubit), PCR/RT-PCR, qPCR.
- Extensive expertise in NGS technologies and workflows, including library preparation and sequencing (in particular the Illumina or Ultima platform)
- Experience with high-throughput molecular workflows
- Experience with LIMS/ELN systems
- Demonstrated problem solving skills and ability to troubleshoot technical issues
- Experience with single-cell RNA-sequencing using the 10x Genomics or other platforms
- Experience with automation platforms
Responsibilities
- Work with both established and emerging sequencing technologies at the forefront of genomics innovation
- Scale up genomic sequencing capabilities to meet growing internal demand
- Contribute to the integration and optimization of new Ultima sequencing platforms into production-level workflows and ramp up throughput operations to reach maximum capacity across multiple instruments
- Onboard and validate new sequencing platforms, ensuring seamless process integration
- Support large institutional genomic initiatives through efficient workflow execution and quality management
- Drive continuous improvement of data integration workflows and laboratory procedures
- Perform NGS library management, pool strategies, and quality evaluation; manage sequencing submissions
Other
- highly skilled, motivated, well-organized, and technically proficient
- You love science and learning.
- You are flexible and adaptable, eager to try new ways of tackling problems beyond the approaches with which you’re familiar while also bringing energy and curiosity to the optimization of existing approaches.
- You can work fast and are detail-oriented. You are careful and diligent about good documentation practices and keeping things organized while moving at a rapid pace.
- You show initiative and can effectively work independently while also adapting well to situations where collaboration and communication with other RAs / Scientists will bring the best results.
