Legend Biotech is seeking a Senior Research Associate, In Vivo Pharmacology (Contractor) to perform preclinical in vivo pharmacology and toxicology studies to support pipeline advancement for treating life-threatening diseases.
Requirements
- Cell culture and cell-based function analysis.
- Experience in ELISA and flow-cytometry is required.
- In vivo study experience is required.
- Being able to handle mice confidently is essential.
- Molecular biology skills such as DNA and RNA extraction, RT-PCR and ddPCR, etc.
- Mouse handling and procedures (bleeding, injection, in vivo imaging, tissue dissection and analysis), cell culture and function analysis, multiple-color flow cytometry, ELISA, qPCR, and multiplexed cytokine analysis assays (MSD and Luminex).
- Not allergic to lab animals.
Responsibilities
- Work together with other team members to execute various in vitro experiments including cell culture and cell functional analysis, human PBMC isolation, ddPCR, flow-cytometry analysis for biomarkers.
- Support in vivo animal studies including management of mouse colony, test article dosing through injections of intravenous, intraperitoneal and subcutaneous.
- Tumor measurement through caliber and bioluminescent imaging, processing and analyzing various animal samples, including blood, tumor and tissues from mice and NHP.
- Lab instrument maintenance.
Other
- Master’s or bachelor’s degree in biological sciences (Immunology, cell biology and cancer biology, et.al.).
- 5 years’ experience in a biological laboratory setting (industry preferred).
- Sense of ownership and integrity of their work.
- Demonstrated ability to work as part of a team.
- Demonstrated organizational skills including but not limited to pay attention to details and multitasking.
