Apriori Bio is seeking to lay the foundation for Global Pathogen Shield™ protective interventions that can neutralize a wide range of the most dangerous and rapidly evolving infectious pathogen threats by developing a revolutionary approach and R&D platform.
Requirements
- Direct experience with NGS-based screening
- Direct experience generating dose response curves
- Direct experience with pooled library screening
- Experience with molecular cloning, qPCR, and sequence analysis
- Experience using Next Gen Sequencing to screen pooled libraries, including virus-like particles
- Experience with RNA and RNA viruses is a plus
- Experience with vaccines, virology and AI is also desirable
Responsibilities
- Perform critical data-generating experiments
- Execute NGS-based sera neutralization assays of pooled virus-like particles
- Execute and optimize cell culture processes for library production to achieve high quality and high yields of vectors
- Implement strategies to increase throughput of sera screening
- Effectively capture experimental protocols and data in an ELN
- Conduct experiments, analyze data, and troubleshoot to improve NGS workflow
- Work closely with molecular virologists and data scientists to support the design and deployment of innovative, proprietary assays
Other
- Collaboration with a matrixed team of scientists and data scientists to deliver on the company platform and pipeline goals.
- Help build the infrastructure of laboratory protocols, tools, and systems to enable focused and rapid discovery and early pipeline development.
- Communicate insights and conclusions to the scientific team and executive management.
- Entrepreneurial spirit, strong communication skills, and comfort working in and contributing to a dynamic and cross-functional team environment.
- The level of the role will be commensurate with the education and years of experience of the identified candidate.
