Glyphic Biotechnologies is developing a massively parallel, single-molecule proteome sequencing platform to transform life science discovery and usher in a new era of insights into human biology and disease.
Requirements
- Experience with bioconjugation methods (e.g., nucleic acids, proteins/peptides, surface coupling).
- Solid foundation in molecular biology techniques and next-generation sequencing, with a preference for Nanopore technologies.
- Deep understanding and hands-on experience with spectroscopic analytical tools (e.g., fluorescence, UV-Vis, flow cytometry, FTIR).
- Proficiency with automation platforms for liquid handling (e.g. Hamilton, ThermoFisher, Agilent).
- Familiarity with separation science (e.g. Chromatography, electrophoresis, liquid-liquid phase separation)
- Familiarity with surface chemistry for flow cells or solid supports.
- Hands-on experience with HPLC, LC-MS, or capillary electrophoresis.
Responsibilities
- Optimize assay workflows to support single-molecule sequencing, ensuring robustness and reproducibility.
- Design and execute experiments bridging chemistry and molecular biology.
- Partner with engineers to run and refine automated protocols that increase throughput and consistency.
- Collaborate with cross-functional teams to troubleshoot, problem-solve, and integrate new processes into the sequencing workflow.
- Analyze experimental data, generate detailed reports, and provide actionable insights to guide further development.
- Apply statistical methods and process evaluation tools to ensure workflow quality and performance.
- Prepare and maintain comprehensive documentation of protocols, SOPs, and results.
Other
- 3+ years of industry or equivalent experience in assay or process development.
- Excellent problem-solving skills and attention to detail.
- Excellent written and verbal communication skills, with the ability to work seamlessly with colleagues from diverse scientific and technical backgrounds.
- Ability to thrive in a fast-paced environment with evolving priorities.
- Excellent interpersonal skills – capable of building strong relationships and communicating effectively with stakeholders at all levels.
