NewLimit is seeking to develop medicines to treat age-related diseases by reprogramming the epigenome, and is looking for a Senior/Research Associate to join their Single Cell Technology group to support this effort
Requirements
- Experience with standard molecular biology workflows (e.g., nucleic acid extraction, PCR, NGS library construction, library quantification and QC)
- Experience with cell and sample handling (e.g., mammalian cell culture, primary tissue dissociation, nuclei isolation, cryopreservation)
- Experience operating a next generation sequencing instrument
- Experience with single cell genomics methods (such as 10x Genomics, PIP-seq, Scale Bio, Parse Bio, Mission Bio, Drop-seq, Perturb-seq/CROProp-seq or similar)
- Experience troubleshooting or optimizing NGS workflows
- Experience with flow cytometry sorting for single-cell preparations
- Basic computational skills for next-generation sequencing analysis (Python programming, Unix, Seurat/Scanpy)
Responsibilities
- Collaborate with our Epigenetic Editing team to perform large-scale, single cell perturbation experiments with custom chemistries
- Perform state-of-the-art single cell profiling experiments to map epigenetic features of age-related disease and evaluate interventions
- Measure the safety & efficacy of reprogramming medicines with frontier genomics methods
- Isolate, culture, and prepare cells for single cell profiling experiments
Other
- Bachelor’s degree in cell biology, molecular biology, or a related natural science or industry experience
- 2+ years of work experience in a cell or molecular biology laboratory (academic or industry)
- Health, dental, and vision insurance
- 401(k) with company match
- Industry-leading paid time off (PTO) -- 20 days/year for all employees + holidays
