Vir Biotechnology is looking to advance its Drug Product and Device Development group by hiring a Senior Scientist I to provide technical leadership for the development of both liquid and lyophilized formulations across multiple biologic modalities, supporting clinical-stage process development and manufacturing initiatives.
Requirements
- Demonstrated expertise in formulation and drug product development for monoclonal antibodies and biologics required; hands-on experience with lyophilization and prefilled syringe development strongly preferred
- Proficiency in experimental design (DoE), data analysis, and use of statistical programs for formulation screening and optimization.
- Strong working knowledge of analytical methods supporting formulation assessments
- Possess a solid understanding of pharmaceutical development, particularly as related to biological drug development
- Experience authoring development reports, batch records, SOPs, regulatory filings, or other documents
- Previous experience representing Drug Product and formulation on inter-disciplinary teams and with external collaborations
- Experience leading technical projects and mentoring junior team members
Responsibilities
- Scientific leadership of formulation development and process optimization for parenteral dosage forms of monoclonal antibodies and biologics, ensuring robustness, stability, and scalability
- Design and execute in-house laboratory studies, including formulation screening, in-use stability studies, and analytical characterization, leveraging advanced experimental designs (DoE) and statistical methods
- Provide technical direction and oversight for internal and external drug product development and manufacturing activities, including data review, trouble-shooting, and risk assessment
- Lead technical transfer of manufacturing processes at contract manufacturing organizations, managing cross-functional alignment and proactively addressing challenges
- Author and review high-impact technical reports, regulatory submissions, and scientific publications, ensuring clarity, accuracy, and regulatory compliance
- Represent Drug Product and Formulation and Device Development on cross-functional program teams, actively contributing to strategy, timelines, and issue resolution in collaboration with clinical, process development, analytical, quality, and regulatory stakeholders
- Ensure consistent scientific oversight for data generated by internal teams and contract research/manufacturing organizations, upholding best practices and industry standards
Other
- PhD with 5+ years , Master's with 8+ years' or Bachelor's with 10+ years' experience, in Biosciences, Pharmaceutical Technology, Biochemistry, Chemistry, Chemical Engineering, or a related discipline
- This role is located in our San Francisco headquarters with an expectation of at least 3 days per week in office.
- Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.
- All employment decisions at Vir Biotechnology are based on legitimate, non-discriminatory business requirements, job duties and individual qualifications.
- Employment decisions are made without regard to any legally protected characteristics.
