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Senior Scientist I (Machine Learning) - Biologics Cell Culture Development

BioSpace

Salary not specified
Nov 16, 2025
South San Francisco, CA, United States of America
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AbbVie's Biologics CMC Development team is seeking to develop and implement machine learning models for predicting optimal cell culture process performance to advance biologic therapies.

Requirements

  • Must have industry or research experience in developing, implementing, and validating ML models
  • Must have a strong understanding of statistical methods, ML methodologies, and ML frameworks (e.g., Sci-kit Learn, TensorFlow, PyTorch)
  • Must demonstrate programming competency for model implementation in Python or equivalent
  • Must have experience in data visualization tools (e.g., Matplotlib, Plotly) to communicate model finding
  • Proficient with Microsoft Office software and strong familiarity with statistical modelling software/tools (e.g., JMP, SIMCA, Minitab, Design Expert)
  • Prior experience in developing and implementing ML models for biological data is highly desirable
  • Experience in implementing transfer learning is highly desirable

Responsibilities

  • Develop, implement, refine, and validate machine learning (ML) models for predicting cell culture process performance
  • Communicate model findings and suggest experimental strategy and/or workflow improvements to support early- and late-stage development
  • Actively seek out opportunities to optimize our platform or enhance our understanding of cell culture processes using ML models and wet lab experiments
  • Design and execute scalable ambr250, 2L, 50L, 200L and 500L single use bioreactors processes
  • Represent the cell culture development group in cross-functional meetings and collaborate closely with cell line, purification, analytical and formulation development leads to meet project deliverables and timelines
  • Publish or present scientific findings in peer-reviewed journals, internal or external conferences or consortia
  • Display effective organization, verbal written communication skills, and adherence to good documentation practices

Other

  • This position is an onsite role in a lab-based function.
  • To be successful, candidates must enjoy and thrive in an onsite, highly collaborative lab environment with face-to-face cross-functional interactions between scientists.
  • Strong attention to detail; active and quick learner; able to change course quickly as needed; raises the bar and is never satisfied with the status quo; open to suggestions and embraces the ideas of others; collaborative actively builds relationships with others
  • Experienced in authoring peer-reviewed publications, technical reports, regulatory documents, and/or presentations at conferences
  • AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.