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Senior Software Engineer, Prenatal

BillionToOne

$190,081 - $211,201
Dec 22, 2025
Menlo Park, CA, US
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BillionToOne is looking to transform healthcare by making life-changing diagnostics accessible to all, specifically in prenatal and cancer diagnostics, and is seeking a Senior Software Engineer to help build the future of precision medicine

Requirements

  • 5 - 7 years of professional software development experience with a proven track record of delivering complex projects adhering to best practices
  • Deep understanding and experience using web frameworks like Django and FastAPI
  • Strong system design and architecture capabilities, applying domain-driven design to translate complex business domains into clear, scalable service and data boundaries
  • Familiarity with modern AI-driven development practices and tools
  • Strong foundation in cloud services, preferably AWS, including ECS, S3, AWS Batch, EC2, and AWS Lambda, enabling effective architecture and management of complex systems
  • Experience with Python, Django, Postgres, React, Typescript, AWS, Heroku, Salesforce, and emerging AI-assisted coding environments (e.g., Cursor, GitHub Copilot, Claude Code)

Responsibilities

  • Design, build, and operate scalable, high availability backend services, APIs, and data integrations that power customer facing product experiences
  • Lead technical delivery across the full lifecycle: architecture, design, implementation, testing, deployment, and ongoing operations
  • Collaborate closely with product, design, and cross functional engineering teams to deliver performant, reliable, and intuitive platform capabilities
  • Develop clean abstractions and platform APIs that simplify complex LIS workflows while balancing developer velocity with long term system stability
  • Build and maintain secure, reliable cloud infrastructure on AWS, including compute environments, networking, container orchestration, storage, and environment automation
  • Implement CI/CD pipelines, Infrastructure as Code, configuration management, and automated environment provisioning to standardize and accelerate delivery
  • Embed observability and operational excellence into the platform by default through robust monitoring, logging, alerting, and reliability patterns

Other

  • Excited about working in-person with our team in Menlo Park
  • Excellent communication and collaboration skills, with the ability to work effectively in a team-oriented environment
  • Bachelor's degree or higher in Computer Science or related field
  • Ability to work in a fast-paced entrepreneurial environment
  • Commitment to changing the standard of care in prenatal and cancer diagnostics