The Department of OB/GYN seeks a Life Science Research Professional 1 to assist with research projects involving the treatment of stress urinary incontinence or pelvic floor prolapse with stem cells and understanding the basic pathophysiology of pelvic floor disorders.
Requirements
- techniques of molecular biology
- tissue culture
- qPCR
- RNA extraction
- General understanding of scientific principles.
- Demonstrated performance to use knowledge and skills when needed.
- Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
Responsibilities
- Assisting senior laboratory members in the preparation and analysis of hiPSC reprogramming with mRNA/RNA method, expansion, banking and characterization of these new derived hiPSC lines, differentiation to smooth muscle cell progenitors (pSMCs) differentiated from autologous iPSCs and then prepared for injection into the urethral sphincter of the small animals to aid regeneration of a deficient urethral sphincter muscle.
- Independently conduct experiments; maintain detailed records of experiments and outcomes.
- Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
- Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
- Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
- Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
- Assist with orientation and training of new staff or students on lab procedures or techniques.
Other
- The LSRP1 will assist multiple projects and must manage time efficiently in doing so.
- The LSRP1 will work independently under general guidance from the scientist and must have the ability to recognize irregularities in experimental results and modify experiments as needed.
- The LSRP1 will order supplies and prepare some reagents for use by other members of the lab and will train new researchers in basic protocol, fluorescence activated cell sorting (FACS) analysis.
- Due to the nature of the lab's work, some experiments the LSRP will manage may deviate from a standard work day.
- Bachelor's degree in related scientific field.
