BridgeBio aims to accelerate therapeutic discovery in rare and genetically defined diseases by pioneering a "moneyball for biotech" approach, pooling early-stage research to reduce risk and unleash innovation. They seek to build bridges to groundbreaking advancements and develop life-changing medicines for patients with unmet needs.
Requirements
- Broad experience across computational biology, with strength in structural biology and/or proteomics and the ability to connect across diverse modalities
- Strong Python software development skills, including package development or contributions to shared repositories with multiple collaborators
- Solid grounding in statistics and data science, with experience analyzing high-dimensional biological data
- Familiarity with AI/ML approaches for data exploration or interpretation, with sound judgment on when and how to apply them
- 3+ years of postdoctoral or industry experience working with large-scale human omics data
Responsibilities
- Design and execute computational analyses focused on structural biology and proteomics, while routinely extending to additional omics and data domains
- Develop and maintain robust Python codebases and packages that support reproducible and scalable analyses
- Apply statistical and computational methods, including selective use of AI/ML where appropriate, to derive interpretable biological insights
- Work independently to define analytical goals, prioritize efforts, and deliver solutions that advance translational and program objectives
- Stay current with evolving multi-omics technologies and computational tools, introducing innovative methods where they can add value
- Communicate key findings clearly through reports, visualizations, and presentations to technical and non-technical audiences
- Lead integrative, multi-omics analyses spanning structural biology, proteomics, and other data types to accelerate therapeutic discovery in rare and genetically defined diseases.
Other
- Ph.D. in Computational Biology, Bioinformatics, Structural Biology, Systems Biology, Data Science, or a related field
- Proven ability to work independently, take initiative, and drive projects from concept to completion
- Excellent communication skills and ability to deliver results in a fast-moving, cross-disciplinary environment
- U.S.-based remote role with periodic travel (quarterly or as needed) to BridgeBio’s San Francisco office or conference locations.
