Twist Bioscience is seeking to expand its antibody characterization department to ensure project-specific deliverables are met across a diverse panel of discovery campaigns and contract services.
Requirements
- Strong understanding of antibody discovery, preferably focusing on assay development and protein characterization
- Previous experience with SPR is required. Experience with Carterra instrument preferred
- Previous experience with BLI is strongly preferred.
- Experience with cell culture preferred.
- Direct experience with ELISA and multicolor flow cytometry is advantageous.
- Ability to effectively troubleshoot and optimize processes in order to meet a wide range of project needs.
Responsibilities
- Developing, running, and troubleshooting antibody characterization experiments using advanced label-free analytical techniques (e.g. BLI and SPR) in a variety of formats to evaluate binding kinetics, ligand blocking, and binning
- Performing titer testing, screening, and antibody validation by ELISA and high throughput multicolor flow cytometry
- Running and troubleshooting cell-based functional assays
- Sample handling, sample inventory tracking and assisting with automation integration into the department
- Concurrently execute multiple antibody discovery projects requiring wet lab activities, data analysis, report generation and preparation of deliverables
- Record and communicate experimental details, draft reports, and deliver data with a high level of integrity and ethics
Other
- Bachelor's degree in molecular biology, biochemistry, or a related discipline with a minimum of 4-5 years of related experience
- Ability to work independently, but also collaborate and effectively communicate within and across departmental teams
- Exceptional written and verbal communication skills
- Highly organized, detail oriented and able to operate in a fast-paced and growing environment
- 3 years experience with MS
