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Staff Machine Learning and Bioinformatics Scientist

Natera

$192,600 - $240,750
Aug 22, 2025
San Carlos, CA, US
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Natera is seeking a Lead/Staff Machine Learning and Bioinformatics Scientist to implement and expand state-of-the-art machine learning methods to enhance their product portfolio in oncology, specifically focusing on Epigenomics.

Requirements

  • Demonstrated experience in developing core ML models, including generalized linear models, kernel methods, tree-based algorithms, and neural networks, with a focus on biological data (e.g., DNA sequencing data)
  • Profound understanding of deep learning models, large language models (LLMs), and multimodal foundation models
  • Proficient in Python and its scientific computing ecosystem (e.g., NumPy, Pandas, Scikit-learn)
  • Experience with ML frameworks such as PyTorch, TensorFlow, or JAX; familiarity with LLM-specific tools like LangChain; and model deployment via platforms like HuggingFace

Responsibilities

  • Develop and validate cutting-edge machine learning methods to solve problems in diagnostics
  • Contribute to model interpretability, uncertainty estimation, and reproducibility best practices
  • Design robust feature engineering and extraction pipelines tailored to biological data
  • Prototype and productionize models using scalable ML infrastructure tools such as MLflow, Airflow, and Docker
  • Collaborate closely with molecular biologists on experimental design and quality control
  • Actively participate in code and design reviews

Other

  • PhD in Computer Science, Statistics, Bioinformatics, or a related quantitative field with 6-12 years of experience post-PhD.
  • Excellent cross-functional communication skills
  • A strong eagerness to both teach and learn about new machine learning methods and biology concepts
  • Position is available as a hybrid position in San Carlos, Bay Area, California as well as a remote position (within US).