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Staff Software Engineer (AI/ML)

Onos Health

Salary not specified
Dec 17, 2025
San Francisco, CA, US
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Onos Health is addressing the 30% of total U.S. healthcare spending that is wasted due to ineffective care and administrative burden caused by misalignment between providers and payers by building an AI-driven healthcare data platform.

Requirements

  • 5+ years experience building and deploying machine learning systems in production
  • Significant experience working with data pipelines and Python and related data science/ML libraries
  • Experience with developing LLM-based systems and integrating them with user-facing features
  • Deep understanding of the limitations of using LLMs and the best practices for using them for reliable, consistent, and accurate outputs
  • Experience wearing multiple hats as a generalist backend engineer
  • Significant experience working with healthcare data and with HIPAA best practices
  • Experience with explainable AI and model governance in regulated industries

Responsibilities

  • Design, develop and deploy sophisticated ML models to analyze healthcare data and detect anomalies, classify patients according to level-of-care guidelines, and make accurate recommendations
  • Develop LLM/NLU systems to process and extract meaningful information from clinical notes and medical documents
  • Build data pipelines that scale efficiently while maintaining strict data privacy and security standards
  • Establish machine learning & AI best practices, evaluation frameworks, and model governance for future team growth
  • Collaborate with backend engineers to integrate AI/ML capabilities seamlessly into the Onos platform
  • Build AI/ML pipelines to analyze medical records to streamline clinical assessments and healthcare quality reviews
  • Design explainable AI solutions that provide transparency into model decisions for healthcare professionals

Other

  • Motivated to meaningfully improve the way healthcare is administered in the United States
  • Customer obsessed and motivated to make an impact in the healthcare space
  • A collaborative team player with a focus on delivering measurable results
  • Hybrid role based in San Francisco, where you'll be expected to work at our office in person 2-3 times a week.
  • Significant responsibility and autonomy from day one